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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: STIP1 All Species: 35.15
Human Site: S459 Identified Species: 55.24
UniProt: P31948 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P31948 NP_006810.1 543 62639 S459 Q K A L D L D S S C K E A A D
Chimpanzee Pan troglodytes XP_001163388 590 68062 S506 Q K A L D L D S S C K E A A D
Rhesus Macaque Macaca mulatta XP_001115389 545 62710 S461 Q K A L D L D S S C K E A A D
Dog Lupus familis XP_854960 543 62542 S459 Q K A L D L D S N C K E A A D
Cat Felis silvestris
Mouse Mus musculus Q60864 543 62564 S459 Q K A L D L D S S C K E A A D
Rat Rattus norvegicus O35814 543 62552 S459 Q K A L D L D S S C K E A A D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511150 518 59858 S434 Q K A L D L D S N C K E A A D
Chicken Gallus gallus
Frog Xenopus laevis NP_001080263 543 62088 S459 Q K A M E L D S T S K E A T D
Zebra Danio Brachydanio rerio NP_001007767 542 61650 S458 Q K A L E L D S N S K E A T E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_477354 490 55680 P409 Q K A L E L D P N N A E A I E
Honey Bee Apis mellifera XP_623766 485 55458 P404 Q K A L E L D P S N S E A L E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002329902 577 65196 P487 Q E G L K H D P H N Q D L L D
Maize Zea mays NP_001151932 581 65529 P491 Q A G L K H D P K N Q E L L D
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_176461 571 64501 P481 Q K G L E H D P N N Q E L L D
Baker's Yeast Sacchar. cerevisiae P15705 589 66247 A495 D A A R T K D A E V N N G S S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 92 95 97.6 N.A. 97.4 97.6 N.A. 89.5 N.A. 86.7 80.1 N.A. 48.7 50.8 N.A. N.A.
Protein Similarity: 100 92 97.2 99.2 N.A. 98.9 98.9 N.A. 93.5 N.A. 93.9 91.5 N.A. 64.8 67.7 N.A. N.A.
P-Site Identity: 100 100 100 93.3 N.A. 100 100 N.A. 93.3 N.A. 66.6 66.6 N.A. 53.3 60 N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 N.A. 86.6 86.6 N.A. 73.3 73.3 N.A. N.A.
Percent
Protein Identity: 46.1 45.7 N.A. 45.8 39.3 N.A.
Protein Similarity: 64.1 62.9 N.A. 64.8 57.5 N.A.
P-Site Identity: 26.6 33.3 N.A. 40 13.3 N.A.
P-Site Similarity: 46.6 40 N.A. 60 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 14 80 0 0 0 0 7 0 0 7 0 74 47 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 47 0 0 0 0 0 % C
% Asp: 7 0 0 0 47 0 100 0 0 0 0 7 0 0 74 % D
% Glu: 0 7 0 0 34 0 0 0 7 0 0 87 0 0 20 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 20 0 0 0 0 0 0 0 0 0 7 0 0 % G
% His: 0 0 0 0 0 20 0 0 7 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % I
% Lys: 0 80 0 0 14 7 0 0 7 0 60 0 0 0 0 % K
% Leu: 0 0 0 87 0 74 0 0 0 0 0 0 20 27 0 % L
% Met: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 34 34 7 7 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 34 0 0 0 0 0 0 0 % P
% Gln: 94 0 0 0 0 0 0 0 0 0 20 0 0 0 0 % Q
% Arg: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 60 40 14 7 0 0 7 7 % S
% Thr: 0 0 0 0 7 0 0 0 7 0 0 0 0 14 0 % T
% Val: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _